THE BASIC PRINCIPLES OF MAKATUSSIN SYROP

desvenlafaxine will improve the degree or influence of codeine by impacting hepatic enzyme CYP2D6 metabolism. Use Warning/Check. Desvenlafaxine inhibits CYP2D6; with larger desvenlafaxine doses (ie, four hundred mg) decrease the CYP2D6 substrate dose by nearly 50%; no dosage adjustment essential with desvenlafaxine doses 7 consecutive days promptly